2012
《Molecular Cell》
Genome-wide Methylation Profiles Reveal Quantitative Views of
Human Aging Rates
2014
《PNAS》
Noninvasive prenatal diagnosis of common
aneuploidies by semiconductor sequencing
2017
《PNAS》,《Nature Materials》
DNA methylation markers for diagnosis and
prognosis of common cancers
Circulating tumour DNA methylation markers for
diagnosis and prognosis of hepatocellular carcinoma
2018
《Cell》
Identifying Medical Diagnoses and Treatable
Diseases by Image-Based Deep Learning
2020
《Science Translational Medicine》
Circulating tumor DNA methylation profiles enable early diagnosis,
prognosis prediction, and screening for colorectal cancer
2021
《Nature Communications》, 《CLINICAL CANCER RESEARCH》
Cellular Heterogeneity-Adjusted cLonal
Methylation (CHALM) improves prediction of gene expression
EpiPanGI Dx: A Cell-free DNA Methylation Fingerprint for
the Early Detection of Gastrointestinal Cancers
2022
《Hepatology Communications》
A multi- analyte cell- free DNA– based blood test for early
detection of hepatocellular carcinoma
"Methylation Technology, 3000+Marker, BioShine Algorithm" Strong patent portfolio moat
2015
Method and system for determining cancer status
2016
Solid tumor methylation markers and uses thereof
Colon cancer methylation markers and uses thereof
Lung cancer methylation markers and uses thereof
Leukemia methylation markers
Breast and ovarian cancer methylation markers
Liver cancer methylation markers
2017
Methylation markers for diagnosing hepatocellular carcinoma
and lung cancer
2018
Methylation markers for diagnosing cancer
2021
CHALM for DNA methylation
